Archivo de marzo, 2015

The European Commission Will Finance the Training of Researchers in Glycoscience

The European Commission has granted funding for an Innovative Training Network within the  Marie Sklodowska-Curie – Horizon 2020 programme, whose goal is to train scientists in biomedical Glycoscience, which focuses on the study of the structural and functional roles of carbohydrates in their biological context. Glycoscience has an increasing impact on many areas of our economy but particularly in biotechnology, health, food and energy, key focus areas also of the Horizon 2020 program.

Illustrative examples for the importance of Glycoscience are the effects of protein glycosylation on efficacy, immunogenicity and circulatory half-life of recombinant therapeutic proteins and the enormous untapped potential of glycan biomarkers in personalized medicine. Most importantly, the therapeutic use of carbohydrate antigens that activate specific receptors on antigen presenting cells like dendritic cells or macrophages shaping the immune response finds wide applications in the development of synthetic vaccines and for the immunotherapy of cancer, allergy and autoimmune diseases.

The IMMUNOSHAPE project, which will be coordinated by CIC biomaGUNE, brings together 14 leading European academic and industrial partners implementing a multidisciplinary and multisectorial training programme in a transnational network in the fields of biomedical glycoscience and its industrial applications. 13 of those centres will host 15 young researchers from different backgrounds, including organic chemistry, biochemistry, structural biology, molecular biology, pharmacy or biophysics. They will develop their PhD projects in areas such as carbohydrate chemistry, chemical synthesis, structural glycobiology, glycotechnology and glyco-functionalization of nanoparticles, among others. The selected candidates will obtain a three-year contract, during which mobility between the 14 institutions in the network will be encouraged in order to enhance synergies between the different participants.

The trained researchers within Immunoshape will be capable of combining state of the art synthesis and the use of cutting-edge technologies to develop the lead structures for highly selective glycan based multivalent immunotherapeutics that may prove useful in treatments for cancer, autoimmune diseases and allergies.

For application procedures, deadlines and further information, please visit www.immunoshape.eu.

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The European Commission Will Finance the Training of a New Generation of Researchers in Leishmaniasis

The European Commission has granted funding for an Innovative Training Network within the  Marie Sklodowska-Curie – Horizon 2020 programme, whose goal is to form the next generation of scientists that will contribute to the control of leishmaniasis. The EUROLEISH-NET project, which will be coordinated by CRESIB/ISGlobal, is multi- and inter-disciplinary since it includes basic, clinical and translational research to propose integrated solutions in the diagnosis, treatment and prevention of leishmaniasis worldwide. Nine public and private European excellence centres will host 15 young researchers from different backgrounds, including molecular biology, epidemiology, medicine, veterinary and health economy. In addition, 19 institutions or companies in and outside Europe will contribute to the formation of the young trainees by offering research visits and know how.

An important aspect of the Project will be the selection of the students developing the 15 PhD projects that include areas such as drug development, vaccines, diagnostic tools, genetic population studies, vector control and integrated control programmes. The selected candidates will obtain a three-year contract, during which mobility between the 28 institutions in the network will be encouraged in order to enhance synergies between the different participants.

Leishmaniasis is considered a neglected infectious disease by the World Health Organization (WHO) and causes an estimated 1.3 million new cases and between 20,000 and 30,000 deaths every year. The disease is caused by a unicellular parasite of the Leishmania genus, is transmitted by the sand fly bite and affects both humans and domestic animals. Although it is globally distributed in South America, Africa, Asia and Europe, it is particularly prevalent among poor communities of developing countries since the major risk factors are poverty, malnutrition, population mobility, environmental changes and climate change. It is the only endemic neglected tropical disease in Europe, where it is mainly a veterinary problem but represents a public health risk.

Leishmaniasis can be treated and cured. However, global control of the disease requires the development of new strategies and tools that go from the laboratory to the bedside and the community. This is precisely the objective of EUROLEISH-NET.

Further information and applications via www.euroleish.net (deadline for applications 5th April 2015)

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14 PhD studentships available in TRUSS (Training in Reducing Uncertainty in Structural Safety)

The growth of cities, impacts of climate change and the massive cost of providing new infrastructure provide the impetus for TRUSS (2015-2018, http://trussITN.eu) which aims to maximize the potential of infrastructure that already exists. If flaws in a structure can be identified early, the cost of repair will be vastly reduced, and here an effective monitoring system would allow identifying the optimum time to repair as well as improving structural safety. But safety is difficult to quantify and requires a deep understanding of the uncertainty associated to measurements and models for the structure and loads. For that purpose, TRUSS brings together an intersectoral and multidisciplinary collaboration between 4 Universities, 11 Industry participants and 1 research institute from 5 European countries. The consortium shares expertise and offers training at an advanced level to qualify graduates for dealing with the challenges of an aging infrastructure stock.

 

TRUSS offers highly competitive and attractive salary and working conditions. There are 14 Early Stage Researchers (PhD students) positions starting in August or September 2015. Each position is for a period of 36 months. The recruitment is done on a competitive basis across all applicants for the projects (note host country for eligibility purposes):

  1. Reliability of concrete structures reinforced with braided FRP (Host: UCD, Ireland);
  2. Reduction of uncertainty in assessing concrete strength of existing structures (Host: Ove Arup, Ireland);
  3. Reduction of uncertainty in design of free standing nuclear spent fuel rack (Host: ENSA, Spain);
  4. Optimization of the design of offshore wind turbine towers (Host TCD, Ireland);
  5. Integrity management of ship structures (Host: Lloyd’s Register, United Kingdom);
  6. Residual life assessment and management of ship unloaders (Host: Lloyd’s Register, United Kingdom);
  7. Railway Weigh-In-Motion for bridge safety (Host: FSDL, United Kingdom);
  8. Probabilistic modelling of bridge damage based on damage indicators (Host: Phimeca, France);
  9. Railway bridge condition monitoring and fault diagnostics (Host: UNOTT, United Kingdom);
  10. Assessment of bridge condition and safety based on measured vibration level (Host: UPC, Spain);
  11. Development of optical fibre distributed sensing for SHM of bridges and large scale structures (Host: UPC, Spain);
  12. Bridge damage detection using an instrumented vehicle (Host: UCD, Ireland);
  13. Using truck sensors for road pavement performance investigation (Host: UNOTT, United Kingdom);
  14. Reduction of uncertainty through regularized, automated road inspection (Host: UCD, Ireland).

More information about the application procedure here

ITN website: http://trussitn.eu/

 

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