{"id":131707,"date":"2010-04-19T08:31:53","date_gmt":"2010-04-19T07:31:53","guid":{"rendered":"http:\/\/www.madrimasd.org\/blogs\/biologia_pensamiento\/?p=131707"},"modified":"2012-01-11T19:05:26","modified_gmt":"2012-01-11T17:05:26","slug":"lamarck-rehabilitado","status":"publish","type":"post","link":"https:\/\/www.madrimasd.org\/blogs\/biologia_pensamiento\/2010\/04\/19\/131707","title":{"rendered":"Lamarck rehabilitado"},"content":{"rendered":"

Lo revolucionario es siempre el pensamiento; no hay otra cosa que el
\npensamiento para revolucionar.<\/em><\/p>\n

Juan Benet. Cartograf\u00eda personal. p 132. Cuatro Ediciones. Valladolid 1997<\/p>\n

\"\"<\/p>\n

Linaria lamarckiana<\/em>. Tomada de Waste magazine<\/a><\/p>\n

Es un placer anunciar hoy\u00a0 la tan esperada rehabilitaci\u00f3n de Lamarck.\u00a0 La\u00a0 investigaci\u00f3n molecular de los mecanismos de herencia de caracteres adquiridos convertida\u00a0 en realidad.<\/p>\n

En el resumen de su art\u00edculo \u00abInheritance of acquired traits in plants (Reinstatement of Lamarck)\u00bb , publicado en Plant Signalling and Behaviour<\/a> este mes de abril de 2010, Hiroshi Sano explica:<\/p>\n

Since Lamarck proposed the idea of inheritance of acquired traits 200 years ago, much has been said for and against it, but the theory was finally declined after the 1930s. Despite of the negative opinions of the majority of geneticists, botanists and plant breeders have long recognized that altered properties during the growth were occasionally transmitted to the offspring. This was also the case with artificially altered properties such as dwarfism, flowering timing and plant stature, which were induced by a non-mutagenic chemical, 5-azacytidine and its derivatives. As these drugs are powerful inhibitors of DNA methylation in vivo, a close correlation between methylation and phenotypic expression was suggested. Subsequent studies showed that rice plants acquired disease resistance upon demethylation of the corresponding resistant gene, and that both resistant trait and hypomethylated status were inherited by the progeny up to 9 generations. Whether or not the methylation pattern changes under natural condition was then questioned, and recent studies have indicated that it indeed naturally changes in response to environmental stresses. Whether or not the altered methylation pattern during the vegetative growth is heritable was also questioned, and studies on toadflax and rice affirmed the question, showing stable maintenance of hypermethylation in the former and hypomethylation in the latter for 250 and 10 years, respectively. The observation strongly suggested that acquired traits can be heritable as far as the acquired methylation pattern is stably transmitted. This concept is consistent with the Lamarck\u2019s theory of the inheritance of acquired traits, which therefore should be carefully reevaluated to reestablish his impaired reputation.<\/em><\/p>\n

Lo cual traduzco as\u00ed:<\/p>\n

Desde que Lamarck propuso la idea de la herencia de caracteres adquiridos hace 200 a\u00f1os, mucho se ha hablado a favor y en contra, pero la teor\u00eda fu\u00e9 finalmente rechazada despu\u00e9s de la d\u00e9cada de 1930. A pesar de las opiniones negativas de la mayor\u00eda de los genetistas, bot\u00e1nicos y mejoradores de plantas han reconocido desde hace tiempo que las propiedades alteradas durante el crecimiento de vez en cuando se transmitieron a la descendencia.
\nEste fue tambi\u00e9n el caso con propiedades alteradas artificialmente tales como enanismo, tiempo de floraci\u00f3n y altura de las plantas, que fueron inducidas por una sustancia qu\u00edmica no mutag\u00e9nica, 5 azacitidina y sus derivados. Dado que estos f\u00e1rmacos son inhibidores potentes de la metilaci\u00f3n del DNA en vivo, esto indicaba una estrecha correlaci\u00f3n entre la mutilaci\u00f3n y la expresi\u00f3n fenot\u00edpica. Estudios posteriores mostraron que plantas de arroz adquir\u00edan resistencia a enfermedades por desmetilaci\u00f3n del gen de resistencia correspondiente, y que tanto la resistencia como el estado hipometilados se heredaban por la progenie hasta nueve generaciones. Se cuestionaba entonces si la pauta de mutilaci\u00f3n cambiar\u00eda o no en condiciones naturales, y estudios recientes han indicado que, en efecto, tales cambios ocurren en respuesta a las tensiones ambientales.
\nSe cuestion\u00f3 tambi\u00e9n si alteraciones en el patr\u00f3n de metilaci\u00f3n durante el crecimiento vegetativo podr\u00edan ser heredadas o no. Estudios en Linaria y en el arroz respondieron afirmativamente a la cuesti\u00f3n, mostrando el mantenimiento estable de hipermetilaci\u00f3n en el primero y en el segundo hipometilaci\u00f3n para 250 y 10 a\u00f1os, respectivamente. <\/em><\/p>\n

La observaci\u00f3n sugiri\u00f3 fuertemente que los caracteres adquiridos pueden ser hereditarios en tanto en cuanto el patr\u00f3n de metilaci\u00f3n se transmite establemente.<\/em><\/p>\n

Este concepto es consistente con la teor\u00eda de la de Lamarck de la herencia de los caracteres adquiridos, que por lo tanto deben ser cuidadosamente reevaluada para restablecer su reputaci\u00f3n da\u00f1ada.<\/em><\/p>\n

M\u00e1s entradas sobre Lamarck aqu\u00ed<\/a>. En particular \u00e9sta<\/a>.<\/p>\n

Sobre la herencia de caracteres adquiridos aqu\u00ed<\/a>.<\/p>\n

Blogalaxia:<\/strong> Lamarck<\/span><\/a> lamarckismo<\/span><\/a> caracteres adquiridos<\/span><\/a> herencia de caracteres adquiridos<\/span><\/a> epigen\u00e9tica<\/span><\/a> Lamarck rehabilitado<\/span><\/a> rehabilitaci\u00f3n de Lamarck<\/span><\/a> ~ Technorati:<\/strong> Lamarck<\/span><\/a> lamarckismo<\/span><\/a> caracteres adquiridos<\/span><\/a> herencia de caracteres adquiridos<\/span><\/a> epigen\u00e9tica<\/span><\/a> Lamarck rehabilitado<\/span><\/a> rehabilitaci\u00f3n de Lamarck<\/span><\/a> ~ AgregaX:<\/strong> Lamarck<\/span><\/a> lamarckismo<\/span><\/a> caracteres adquiridos<\/span><\/a> herencia de caracteres adquiridos<\/span><\/a> epigen\u00e9tica<\/span><\/a> Lamarck rehabilitado<\/span><\/a> rehabilitaci\u00f3n de Lamarck<\/span><\/a><\/h6>\n","protected":false},"excerpt":{"rendered":"

Lo revolucionario es siempre el pensamiento; no hay otra cosa que el pensamiento para revolucionar. Juan Benet. Cartograf\u00eda personal. p 132. Cuatro Ediciones. Valladolid 1997 Linaria lamarckiana. Tomada de Waste magazine Es un placer anunciar hoy\u00a0 la tan esperada rehabilitaci\u00f3n de Lamarck.\u00a0 La\u00a0 investigaci\u00f3n molecular de los mecanismos de herencia de caracteres adquiridos convertida\u00a0 en realidad. En el resumen de su art\u00edculo \u00abInheritance of acquired traits in plants (Reinstatement of Lamarck)\u00bb , publicado en Plant Signalling and Behaviour este mes de abril de 2010, Hiroshi Sano explica:<\/p>\n","protected":false},"author":86,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0},"categories":[467,303,468,492,498,453,489,465,493,499,6722,511,515],"tags":[22692,22765],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":4}},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.madrimasd.org\/blogs\/biologia_pensamiento\/wp-json\/wp\/v2\/posts\/131707"}],"collection":[{"href":"https:\/\/www.madrimasd.org\/blogs\/biologia_pensamiento\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.madrimasd.org\/blogs\/biologia_pensamiento\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.madrimasd.org\/blogs\/biologia_pensamiento\/wp-json\/wp\/v2\/users\/86"}],"replies":[{"embeddable":true,"href":"https:\/\/www.madrimasd.org\/blogs\/biologia_pensamiento\/wp-json\/wp\/v2\/comments?post=131707"}],"version-history":[{"count":8,"href":"https:\/\/www.madrimasd.org\/blogs\/biologia_pensamiento\/wp-json\/wp\/v2\/posts\/131707\/revisions"}],"predecessor-version":[{"id":133914,"href":"https:\/\/www.madrimasd.org\/blogs\/biologia_pensamiento\/wp-json\/wp\/v2\/posts\/131707\/revisions\/133914"}],"wp:attachment":[{"href":"https:\/\/www.madrimasd.org\/blogs\/biologia_pensamiento\/wp-json\/wp\/v2\/media?parent=131707"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.madrimasd.org\/blogs\/biologia_pensamiento\/wp-json\/wp\/v2\/categories?post=131707"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.madrimasd.org\/blogs\/biologia_pensamiento\/wp-json\/wp\/v2\/tags?post=131707"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}